25/04 - 20:00
| Date | Time | Home | Away | Matchday | TV | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
D | 2022-01-08 | 03:00 | Puebla |  | 1-1 |  | América | D1 | ||||
L | 2022-01-23 | 03:00 | América | | 0-2 |  | Atlas | D3 | ||||
L | 2022-02-06 | 01:00 | América | | 2-3 |  | Atlético San Luis | D4 | ||||
W | 2022-02-13 | 03:00 | Santos Laguna |  | 2-3 | | América | D5 | ||||
L | 2022-02-17 | 01:00 | Mazatlán |  | 2-1 | | América | D2 | ||||
L | 2022-02-20 | 22:00 | América | | 1-3 |  | Pachuca | D6 | ||||
D | 2022-02-27 | 03:00 | Pumas |  | 0-0 | | América | D7 | ||||
D | 2022-03-02 | 03:00 | América | | 1-1 |  | Querétaro | D8 | ||||
L | 2022-03-05 | Monterrey |  | 2-1 | | América | D9 | |||||
D | 2022-03-13 | 03:00 | Chivas |  | 0-0 | | América | D10 | ||||
W | 2022-03-20 | 23:00 | América | | 3-0 |  | Toluca | D11 | ||||
W | 2022-04-03 | 02:00 | Necaxa |  | 0-1 | | América | D12 | ||||
W | 2022-04-10 | 03:00 | América | | 3-0 |  | Juárez | D13 | ||||
W | 2022-04-16 | 03:06 | Club Tijuana |  | 1-3 | | América | D14 | ||||
W | 2022-04-21 | 03:00 | América | | 2-0 |  | Club León | D15 | ||||
W | 2022-04-24 | 01:00 | Tigres |  | 0-2 | | América | D16 | ||||
D | 2022-05-01 | 03:00 | América | | 0-0 |  | Cruz Azul | D17 | ||||
