25/04 - 20:00
| 2023/12/09 | Columbus Crew |  | 2-1 |  | Los Angeles FC |
| 2023/12/02 | FC Cincinnati |  | 2-3 a.e.t. | | Columbus Crew |
| 2023/12/03 | Los Angeles FC | | 2-0 |  | Houston Dynamo |
| 2023/11/25 | Orlando City |  | 0-2 a.e.t. | | Columbus Crew | ||||
| 2023/11/26 | FC Cincinnati | | 1-0 |  | Philadelphia Union |
| Orlando City | | (2-0) |  | Nashville SC | |||||||
| 1 | 30/10 | 23:00 | Orlando City | 1-0 | Nashville SC | h2h | |||||
| 2 | 08/11 | 02:00 | Nashville SC | 0-1 | Orlando City | h2h | |||||
| Los Angeles FC | | (2-0) |  | Vancouver Whitecaps | |||||||
| 1 | 29/10 | 01:00 | Los Angeles FC | 5-2 | Vancouver Whitecaps | h2h | |||||
| 2 | 06/11 | 00:30 | Vancouver Whitecaps | 0-1 | Los Angeles FC | h2h | |||||
| Philadelphia Union | | (2-0) |  | NE Revolution | |||||||
| 1 | 28/10 | 22:00 | Philadelphia Union | 3-1 | NE Revolution | h2h | |||||
| 2 | 09/11 | 00:00 | NE Revolution | 0-1 | Philadelphia Union | h2h | |||||
| Houston Dynamo | | (2-1) |  | Real Salt Lake | |||||||
| 1 | 29/10 | 22:00 | Houston Dynamo | 2-1 | Real Salt Lake | h2h | |||||
| 2 | 07/11 | 02:00 | Real Salt Lake | 1-1 (5-4 pens) | Houston Dynamo | h2h | |||||
| 3 | 11/11 | 23:00 | Houston Dynamo | 1-1 (4-3 pens) | Real Salt Lake | h2h | |||||
| FC Cincinnati | | (2-0) |  | NY Red Bulls | |||||||
| 1 | 30/10 | 00:00 | FC Cincinnati | 3-0 | NY Red Bulls | h2h | |||||
| 2 | 04/11 | 23:00 | NY Red Bulls | 1-1 (7-8 pens) | FC Cincinnati | h2h | |||||
| St. Louis City SC |  | (0-2) |  | Sporting KC | |||||||
| 1 | 30/10 | 02:10 | St. Louis City SC | 1-4 | Sporting KC | h2h | |||||
| 2 | 05/11 | 22:00 | Sporting KC | 2-1 | St. Louis City SC | h2h | |||||
| Columbus Crew | | (2-1) |  | Atlanta United | |||||||
| 1 | 01/11 | 23:30 | Columbus Crew | 2-0 | Atlanta United | h2h | |||||
| 2 | 08/11 | 00:00 | Atlanta United | 4-2 | Columbus Crew | h2h | |||||
| 3 | 13/11 | 00:00 | Columbus Crew | 4-2 | Atlanta United | h2h | |||||
| Seattle Sounders |  | (2-1) |  | FC Dallas | |||||||
| 1 | 31/10 | 01:00 | Seattle Sounders | 2-0 | FC Dallas | h2h | |||||
| 2 | 05/11 | 01:00 | FC Dallas | 3-1 | Seattle Sounders | h2h | |||||
| 3 | 11/11 | 03:00 | Seattle Sounders | 1-0 | FC Dallas | h2h |
| G | GS | GC | Pts | |||
|---|---|---|---|---|---|---|
| 1 | | FC Cincinnati | 34 | 57 | 39 | 69 |
| 2 | | Orlando City | 34 | 55 | 39 | 63 |
| 3 | | Columbus Crew | 34 | 67 | 46 | 57 |
| 4 | | Philadelphia Union | 34 | 57 | 41 | 55 |
| 5 | | NE Revolution | 34 | 58 | 46 | 55 |
| 6 | | Atlanta United | 34 | 66 | 53 | 51 |
| 7 | | Nashville SC | 34 | 39 | 32 | 49 |
| 8 | | NY Red Bulls | 34 | 36 | 39 | 43 |
| 9 |  | Charlotte FC | 34 | 45 | 52 | 43 |
| 10 |  | CF Montréal | 34 | 36 | 52 | 41 |
| 11 |  | New York City FC | 34 | 35 | 39 | 41 |
| 12 |  | DC United | 34 | 45 | 49 | 40 |
| 13 |  | Chicago Fire | 34 | 39 | 51 | 40 |
| 14 |  | Inter Miami CF | 34 | 41 | 54 | 34 |
| 15 |  | Toronto FC | 34 | 26 | 59 | 22 |
| G | GS | GC | Pts | |||
|---|---|---|---|---|---|---|
| 1 | | St. Louis City SC | 34 | 62 | 45 | 56 |
| 2 | | Seattle Sounders | 34 | 41 | 32 | 53 |
| 3 | | Los Angeles FC | 34 | 54 | 39 | 52 |
| 4 | | Houston Dynamo | 34 | 51 | 38 | 51 |
| 5 | | Real Salt Lake | 34 | 48 | 50 | 50 |
| 6 | | Vancouver Whitecaps | 34 | 55 | 48 | 48 |
| 7 | | FC Dallas | 34 | 41 | 37 | 46 |
| 8 | | Sporting KC | 34 | 48 | 51 | 44 |
| 9 |  | SJ Earthquakes | 34 | 39 | 43 | 44 |
| 10 |  | Portland Timbers | 34 | 46 | 58 | 43 |
| 11 |  | Minnesota United | 34 | 46 | 51 | 41 |
| 12 |  | Austin FC | 34 | 49 | 55 | 39 |
| 13 |  | LA Galaxy | 34 | 51 | 67 | 36 |
| 14 |  | Colorado Rapids | 34 | 26 | 54 | 27 |
 | |
|
| 2 |
|
Cucho Hernández Columbus Crew | 21 G |
| 3 |
|
Giorgos Giakoumakis Atlanta United | 19 G |
| 3 |
|
Luciano Acosta FC Cincinnati | 19 G |
| 5 |
|
Brian White Vancouver Whitecaps | 16 G |
| 2 |
|
Ryan Gauld Vancouver Whitecaps | 14 AST |
| 3 |
|
Héctor Herrera Houston Dynamo | 13 AST |
| 4 |
|
Luciano Acosta FC Cincinnati | 12 AST |
| 4 |
|
Brooks Lennon Atlanta United | 12 AST |
