26/04 - 20:00
| 1981/05/16 | Colo-Colo |  | 5-1 |  | Audax Italiano |
| G | GS | GC | Pts | |||
|---|---|---|---|---|---|---|
| 1 |  | Cobreloa | 8 | 20 | 6 | 13 |
| 2 |  | San Luis de Quillota | 8 | 15 | 14 | 8 |
| 3 |  | Everton | 8 | 18 | 15 | 7 |
| 4 |  | Deportes Iquique | 8 | 15 | 17 | 7 |
| 5 |  | La Serena | 8 | 10 | 26 | 5 |
| G | GS | GC | Pts | |||
|---|---|---|---|---|---|---|
| 1 | | Audax Italiano | 10 | 15 | 9 | 14 |
| 2 | | Colo-Colo | 10 | 15 | 9 | 13 |
| 3 |  | Unión Española | 10 | 14 | 15 | 11 |
| 4 |  | Univ. Católica | 10 | 14 | 12 | 9 |
| 5 |  | Universidad de Chile | 10 | 15 | 16 | 9 |
| 6 |  | Palestino | 10 | 10 | 22 | 4 |
| G | GS | GC | Pts | |||
|---|---|---|---|---|---|---|
| 1 |  | O´Higgins | 8 | 15 | 5 | 16 |
| 2 |  | Los Náuticos | 8 | 9 | 5 | 10 |
| 3 |  | Magallanes | 8 | 10 | 8 | 7 |
| 4 |  | Deportes Concepción | 8 | 10 | 11 | 6 |
| 5 |  | Ñublense | 8 | 4 | 19 | 1 |
