29/04 - 20:00
29/04 - 20:00
30/04 - 20:00
30/04 - 20:00
29/04 - 20:00
29/04 - 20:00
30/04 - 20:00
30/04 - 20:00
| 2022/05/07 | Cruz Azul |  | 1-1 (3-1 pens) |  | Necaxa | ||||
| 2022/05/08 | Monterrey |  | 2-2 (1-3 pens) |  | Atlético San Luis | ||||
| Puebla |  | 2-2 (3-1 pens) |  | Mazatlán | |||||
| 2022/05/09 | Chivas |  | 4-1 |  | Pumas |
| 30/04 | Necaxa | | 0-1 | | Chivas | ||||
| Mazatlán | | 2-1 | | Puebla | |||||
| Querétaro |  | 4-0 |  | Juárez | |||||
| 01/05 | Atlas |  | 1-1 |  | Tigres | ||||
| Monterrey | | 2-0 |  | Club Tijuana | |||||
| América |  | 0-0 | | Cruz Azul | |||||
| Pumas | | 2-0 |  | Pachuca | |||||
| Atlético San Luis | | 1-3 |  | Santos Laguna | |||||
| 02/05 | Club León |  | 4-4 |  | Toluca |
Standings
|
| 2 |
|
André-Pierre Gignac Tigres | 14 G |
| 3 |
|
Julián Quiñones Atlas | 9 G |
| 3 |
|
Rodrigo Aguirre Necaxa | 9 G |
| 5 |
|
Germán Berterame Atlético San Luis | 8 G |
